Scalproller™ Titanium Microneedle Roller

Size: 0.3 mm.
Price: $109.95 ea.


The Scalproller by Nanogen has 4 innovative modes of action to enhance any hair treatment regimen:

1. Increases Topical Treatment Absorption
Scalproller pre-treatment has been shown to increase absorption of topical treatments by 5 times or more. With Scalproller pre-treatment, lower 2% concentrations of a topical treatment solution will give concentrations in the scalp higher than when using 5% solutions on untreated skin. Similarly, 5% solutions will produce higher concentrations in the scalp than 12.5% solutions or suspensions used on untreated skin. Frontal scalp areas are notoriously difficult to treat topically, most probably due to lack of absorption. Therefore topical treatments are only really effective in treating vertex hair loss. Using Nanogen's Scalproller can dramatically increase absorption of topical treatments in these regions, opening up new potential areas for topical treatments to act on.

2. Heals Donor Scars
Hair transplant surgery commonly leaves scars in the donor region; Nanogen's Scalproller has been proven to fade and reduce the appearance of these scars by breaking up scar tissue structures and formations. Plus there is evidence in animal models to show that new hair may grow to conceal the donor area after Scalproller treatment.

3. Activates PRP Treatment
Platelet Rich Plasma or PRP therapy is a cutting edge development in hair loss treatment. PRP has been shown to produce thicker transplanted hair growth, and possibly even thicken non-transplanted hair. In PRP therapy, the platelet and growth factor rich fraction of the patient's blood is re-injected into them, and then growth is activated by repeated needle insertion. Single needle insertion is irregular, time consuming and often painful. Scalproller treatment produces much more reliable, regular needle insertions in less time, and with less pain.

4. Encourages New Hair Growth
The latest research by Intercytex, performed with Dr. Bessam Farjo as principal investigator, has shown that patients receiving superficial injections and controlled wounding grow new hair, which may solely be a result of the controlled skin wounding itself. This surprising result is correlated by the pioneering work published by Dr. George Cotsarelis of Pennsylvania University, who found that stimulation of the Wnt protein by wounding leads to hair regeneration. Wounding by microneedles would potentially start this Wnt protein mediated growth stimulation, and prevent synthesis of TGF-β2, a protein known to induce hair loss.

Scalproller treatment increases topical treatment penetration and may independently promote new hair growth.

Increasing Topical Treatment Penetration

Scalp skin is comprised of several layers. The outside layer is called the stratum corneum, and is made from dead skin cells with a high concentration of oils an keratin protein. This layer protects the outside of the body, and is very effective at preventing microbes and chemicals from passing through, entering the body.

Applying topical treatments is only useful if the actives can penetrate through this layer. Actives that are small molecules can penetrate around the hair shaft and sebaceous glands, and some of the active will go through the stratum corneum. However a significant amount of actives will be blocked, especially larger molecules. This often means that only a fraction of the total active in the product reaches the target area and has an effect.

Using the Scalproller creates thousands of quickly healing channels through the stratum corneum, bypassing the major barrier to treatment absorption. The stratum corneum on the scalp is not very thick, and can be penetrated by a 0.3 or a 0.5mm microneedle. These channels allow more than 5 times more actives to penetrate the scalp. They also allow larger molecules like growth factors to penetrate easily, where before absorption would have been low.


  1. For best results, first cleanse the scalp using Hair Prepare.
  2. Clean the Scalproller with the sanitising solution spray and allow to dry for a few seconds before use.
  3. At first, use a constant, gentle rolling motion once in one direction only over each area, from the crown toward the front or the sides. After time, individual users may prefer to roll in multiple directions.
  4. Apply a topical solution like Serum VEGF as per the product instructions. Use the roller once a day at night before applying topical treatment.
  5. Ensure the roller is cleansed thoroughly after each use, run under hot water and allow to dry before sterilising and returning it to the case. Always allow the roller to cool before using.


What is a Scalproller?
Nanogen's Scalproller is a treatment previously only available through Trichologists or Dermatologists. The 0.3mm & 0.5mm models have now made this treatment available for use at home. It is a cylindrical barrel with precision engineered titanium microneedles which penetrate the top layers of skin without causing damage or bleeding. This accurate and non-intrusive penetration allows much higher absorption of scalp treatments like Serum VEGF. It may also stimulate scalp healing and hair growth by itself as it can stimulate the scalp's healing response.

How will Nanogen's Scalproller Work?
As you roll the roller over your scalp it penetrates the upper layers of skin. By opening the skin in this way you dramatically increase the penetration of any topical growth product, increasing its efficacy. These perforations also stimulate the scalp's healing mechanisms, increasing production of many important factors for a healthy scalp.

Can I use the Scalproller more than once a day?
At first, the Scalproller is designed to be used once daily, and is far more intensive than any skin roller, using more than once daily may be possible after time, depending on the individual. If used more than once a day initially the Scalproller may cause more irritation than is aimed for, and even cause damage.

When using the Scalproller do I roll over each part of my scalp only once?
At first, use a single motion once over each area of scalp, rolling gently forward from the crown. This produces a controlled amount of irritation and avoids tangling the roller in longer hair. After time, individual users may prefer to roll in multiple directions.

Which needle length Scalproller should I use?
Nanogen's genuine Scalproller is available in 2 versions for home use. The 0.3mm version is recommended for patients with very thin hair or pain sensitive skin. A 0.5mm home version is available to ensure penetration even with thicker hair.

Will the Scalproller mark my scalp, cause redness, or cause pain or bleeding?
When used as directed, the Scalproller will only cause small or no marks, and the marks will fade in under a minute. Scalproller treatment may cause a flush to your scalp that will fade in a few hours, but no long-lasting redness. The Scalprollers made available for home use have sharp, durable titanium needles that do not cause appreciable pain or bleeding.

Do I use Nanogen's Scalproller over my whole scalp, or just the thinning area?
As the main aim of the Scalproller is to help topical hair loss treatments penetrate, you should use the Scalproller everywhere that you will apply your topical treatment. However using it elsewhere will certainly not do any harm.

Is this the same as other Skin or Derma Rollers?
No. Other skin rollers have different needle lengths, and are designed to be used for different purposes. Some claim they will work on Hair Loss, but Nanogen's Scalproller is the first specially designed for use on the scalp and for use every day. No other skin roller is made from unique titanium needles, so only the Scalproller can be reused intensively for 3-6 months.

Can I use a topical solution with the Scalproller?
Yes, the Scalproller is designed to be used with topical treatments to increase their efficacy, you should still follow the guidelines on your topical treatments for their application.

When do I use a topical solution with the Scalproller?
You use the Scalproller first, to increase the penetration of the treatment, then the topical treatment. You should still follow the guidelines on your topical treatments for their application.

I use more than one topical solution, which should I apply first?
The same as you did before you used the Scalproller, you should still follow the guidelines on your topical treatments for their application.

How long will the Scalproller last for?
Even when used daily, due to its unique durable titanium microneedles Nanogen's Scalproller can last from 3-6 months.

How do I know when to replace my Scalproller?
There will be no visible signs of the sharpness deteriorating. After 3 months, if you begin to notice any increase in pain or inflammation while using the Scalproller, this is a sign the needles are becoming less sharp, and you need to replace it. After 6 months you should replace your Scalproller, even if you have not noticed a difference in pain or inflammation.

Is Nanogen's Scalproller Guaranteed to Work?
Like all Nanogen products, the Scalproller is manufactured and quality controlled to exacting standards. Unfortunately, due to regulations on handling of biological material, we cannot accept returns of a used Scalproller and so cannot refund the product.

Composition Highlights:

Titanium Microneedles
Most dermatological rollers are designed for use on facial skin and are made from stainless steel, which can blunt easily with daily use on the tougher scalp skin. Nanogen's Scalproller microneedles are engineered in Sweden from pure titanium giving a finer and much more durable edge, eliminating excess irritation caused by ordinary steel needles. Furthermore each individual Scalproller microneedle is gold plated to maintain sterility.

Optimum Microneedle Length
Studies indicate Scalproller needles need to penetrate the upper layer of skin for best results. The Scalproller has a variety of needle lengths for optimum results without appreciable pain or injury.
The genuine Scalproller by Nanogen is available in 2 home versions for home use. At first, a 0.3mm version is recommended for patients without a professional consultation. A 0.5mm home version is available for patients after having used the 0.3mm or after consultation with a medical professional. Since longer needles can cause pain if not used by experts accompanied by topical anaesthetic creams, the Scalproller is also available with a 1.0mm needle length for clinical use only.

Sterile Packaging
The Scalproller is delivered to you in an airtight pack that has been gamma sterilised to ensure complete safety.